Fáìlì:Serpin equilibrium.png
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Àkótán
| Ìjúwe |
English: The native state of serpins is an equilibrium between a fully-stressed state (left) and a partially relaxed state (right). The five-stranded A-sheet (light blue) contains two functionally important regions for the serpin's mechanism, the breach and the shutter. The Reactive Centre Loop (RCL, blue) exists in a dynamic equilibrium between the fully exposed conformation (left) and a conformation where it is partially inserted into the breach of the A-sheet (right). (PDB: 1QLP, 1YXA).
[1] [2] |
| Ọjọ́ọdún | |
| Orísun | Iṣẹ́ onítọ̀hún |
| Olùdá | Thomas Shafee |
Ìwé àṣẹ
Èmi gangan, tó jẹ́ pé èmi ni mo ni ẹ̀tọ́àwòkọ iṣẹ́ yìí, fara mọ́ ọ láti tẹ̀ẹ́jáde lábẹ́ ìwé-àṣẹ ìsàlẹ̀ yìí:
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- Ẹ ní ààyè:
- láti pín pẹ̀lú ẹlòmíràn – láti ṣàwòkọ, pínkiri àti ṣàgbéká iṣẹ́ náà
- láti túndàpọ̀ – láti mulò mọ́ iṣẹ́ míràn
- Lábẹ́ àwọn àdéhùn wọ̀nyí:
- ìdárúkọ – Ẹ gbọdọ̀ ṣe ọ̀wọ̀ tó yẹ, pèsè ìjápọ̀ sí ìwé-àṣe, kí ẹ sì sọ bóyá ìyípadà wáyé. Ẹ le ṣe èyí lórísi ọ̀nà tó bojúmu, sùgbọ́n tí kò ní dà bii pé oníìwé-àṣe fọwọ́ sí yín tàbí lílò yín.
- ↑ Elliott PR, Lomas DA, Carrell RW, Abrahams JP. (1996). "Inhibitory conformation of the reactive loop of alpha 1-antitrypsin". Nature Structural & Molecular Biology 3 (8): 676–81. DOI:10.1038/nsb0896-676. PMID 8756325.
- ↑ (2005). "The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.". J Biol Chem 280 (52): 43168–78. DOI:10.1074/jbc.M505598200. PMID 16141197.
Ìtàn fáìlì
Ẹ kan kliki lórí ọjọ́ọdún/àkókò kan láti wo fáìlì ọ̀ún bó ṣe hàn ní àkókò na.
| Ọjọ́ọdún/Àkókò | Àwòrán kékeré | Àwọn ìwọ̀n | Oníṣe | Àríwí | |
|---|---|---|---|---|---|
| lọ́wọ́ | 23:23, 6 Oṣù Ọ̀wàrà 2016 | | 3,000 × 1,902 (1.41 MB) | Cmdrjameson | Compressed with pngout. Reduced by 772kB (34% decrease). |
| 23:05, 19 Oṣù Ẹ̀rẹ̀nà 2016 |  | 3,000 × 1,902 (2.16 MB) | Evolution and evolvability | Colour tweaks | |
| 12:05, 14 Oṣù Ọ̀pẹ̀ 2015 |  | 1,246 × 765 (476 KB) | Evolution and evolvability | Cross-wiki upload from en.wikipedia.org |
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