Mario Capecchi

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Mario Capecchi

Ìbí Oṣù Kẹ̀wá 6, 1937 (1937-10-06) (ọmọ ọdún 78)
Verona, Italy
Ọmọ orílẹ̀-èdè United States
Pápá Genetics
Ilé-ẹ̀kọ́ Harvard School of Medicine
University of Utah
Ibi ẹ̀kọ́ George School
Antioch College, Ohio
Harvard University
Ó gbajúmọ̀ fún Knockout mouse
Àwọn ẹ̀bùn àyẹ́sí Albert Lasker Award for Basic Medical Research (2001)
Wolf Prize in Medicine (2002)
Nobel Prize in Physiology or Medicine (2007)
Religious stance Quaker

Mario Renato Capecchi (Verona, Italy, bíi Ọjọ́ Kẹfà Oṣù Kẹwa nìnù Ọd́n 1937) jẹ́ onímọ̀ ẹ̀kọ́ molecular genetics ọmọ ilẹ̀ Amẹ́ríkà tí wọ́n bí sí ilẹ̀ Italy tí ó gba Ẹ̀bùn Nobel nínú ìmọ̀ bí ara ṣe ń ṣiṣ́ẹ́ tàbí ìmọ̀ ìjìnlẹ̀ fún ìlera ní ọdún 2007 fún ṣíṣe àwárí ọ̀nà tí a lè gbà dà eku, ní èyí tí a lè pa gene ẹ̀, tí àwọ́n olóyìnbó ń pè ní knockout mice.[1][2][3][4][5] Ó pín èbùn yí pẹ̀lú Martin Evans àti Oliver Smithies.[6]

Àwọn Ìtọ́kasí[àtúnṣe | àtúnṣe àmìọ̀rọ̀]

  1. Thomas, K. R.; Capecchi, M. R. (1987). "Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells". Cell 51 (3): 503–512. doi:10.1016/0092-8674(87)90646-5. PMID 2822260. 
  2. Mansour, S. L.; Thomas, K. R.; Capecchi, M. R. (1988). "Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes". Nature 336 (6197): 348–352. doi:10.1038/336348a0. PMID 3194019. 
  3. Capecchi, M. R. (1980). "High efficiency transformation by direct microinjection of DNA into cultured mammalian cells". Cell 22 (2 Pt 2): 479–488. doi:10.1016/0092-8674(80)90358-x. PMID 6256082. 
  4. Chisaka, O.; Capecchi, M. R. (1991). "Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5". Nature 350 (6318): 473–479. doi:10.1038/350473a0. PMID 1673020. 
  5. Thomas, K. R.; Folger, K. R.; Capecchi, M. R. (1986). "High frequency targeting of genes to specific sites in the mammalian genome". Cell 44 (3): 419–428. doi:10.1016/0092-8674(86)90463-0. PMID 3002636. 
  6. "The Nobel Prize in Physiology or Medicine 2007". Nobelprize.org. http://nobelprize.org/nobel_prizes/medicine/laureates/2007/index.html. Retrieved 2007-10-08.